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NEUROTOXIN 

Also known as Jeuveau, Xeomin, Daxxify, Letybo, Botox, and Dysport, these injectable marvels work wonders by relaxing targeted muscles, to prevent the formation of lines and wrinkles. Experience the transformative effects of our non-invasive tox treatment, boasting results that typically last 3-4 months for most individuals. 

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PRP + PRF REGENERATIVE THERAPY

We offer advanced regenerative treatments using Platelet-Rich Plasma (PRP) and Platelet-Rich Fibrin (PRF) to support natural healing and rejuvenation. Derived from your own blood, these therapies are rich in growth factors that help stimulate tissue repair and collagen production.

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PRP and PRF can be used for facial rejuvenation, hair restoration and joint support (including treatments for the shoulder, knee, and ankle to help improve comfort and function.) We also use these therapies in Sexual Wellness, increasing function and comfort.​ PRF is considered the next generation of PRP, designed to release growth factors more gradually for longer-lasting regenerative benefits.

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PDO THREADS

PDO Threads are a revolutionary non-invasive cosmetic treatment that redefines aging gracefully. Utilizing biodegradable threads made from PDO (polydioxanone), this procedure gently lifts and firms sagging skin, stimulates collagen production, and improves skin texture for a rejuvenated appearance. Whether you desire a subtle enhancement or a dramatic lift, PDO Threads offer customizable solutions tailored to your unique needs.

SKINBOOSTERS

Skin boosters are injectable and topical treatments designed to deeply hydrate, improve skin texture, and restore a healthy glow from within. Unlike traditional dermal fillers that add volume or structure, skin boosters improve skin quality, elasticity, and overall radiance.

 

Common treatment areas include the face, neck, décolleté, and hands - choose TIGHTEN, BRIGHTEN, or HEIGHTEN. Available as injectables or as a microneedling boosters. 

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DERMAL FILLER

Dermal fillers are injectable treatments that restore volume, enhance facial features, smooth wrinkles, and improve overall balance. At 417 Refine, every treatment is fully customized to enhance your natural beauty with subtle, natural-looking results and minimal downtime.

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We treat multiple areas of the face and body, including the cheeks, lips, jawline, chin, nose, neck, hands, earlobes, and body.

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Some of our favorite treatment areas:

  • Cheeks and Midface • Lips • Chin & Jawline

  • Nose (Non-Surgical Rhinoplasty) • Neck & Hands

  • Earlobes • Body (Liquid BBL)

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​RENUVA

Renuva is an advanced filler that restores volume by stimulating your body to replace it with your own fat over time. Results are natural-looking and long-lasting. Ideal for restoring volume and smoothing irregularities in areas where fat naturally exists.
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BIOSTIMULATORS

Biostimulators work by stimulating your body’s natural collagen production to improve firmness, structure, and long-term volume.

  • Radiesse: Provides immediate volume while boosting collagen, great for cheeks, jawline, chin, and hands

  • Hyper-Dilute Radiesse: Improves skin laxity and crepey texture on the neck, chest, arms, and body

  • Sculptra: Gradually restores volume and enhances collagen for long-lasting, natural results (up to 2 years)​​​​​​​​​

 

FAT DISSOLVING THERAPY​​​​

PC/DC (or Kybella) and other breakthrough injectable solutions are for sculpting your ideal profile. Targeting fat in the submental area or under the chin, they offer a non-surgical approach to achieving a more defined jawline. Also used in areas like bra bulge, undesired love handles or upper/lower back fat, abdomen, thighs, or upper arms. ​By directly injecting into adipose tissue, it works to permanently dissolve fat cells, providing lasting results for a more sculpted, contoured appearance.​

 

SCLEROTHERAPY

Our expert medical professionals specialize in this effective treatment, which involves injecting a solution directly into veins, causing them to fade from view. Whether you'd like to target spider veins or larger varicose veins, sclerotherapy offers a non-invasive solution with minimal discomfort and downtime.

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PEPTIDE THERAPY

​Peptides are targeted amino-acid messengers that signal your body to repair, restore, and regenerate. At 417 Refine, our personalized peptide protocols optimize skin health, energy, metabolism, recovery, and overall longevity... supporting you in feeling and functioning at your highest level. 

 

We offer a curated selection of peptides, including GLOW Complex, GHK-Cu, BPC-157, TB-500, the Wolverine Stack, CJC-1295 + Ipamorelin, Sermorelin, Tesamorelin, MOTS-C, NAD+, Melanotan, and more. 

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WEIGHT LOSS OPTIMIZATION

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Embark on your weight loss journey with local support! We offer njectable GLP-1 compounded medications (semaglutide, tirzepetide, retatrutide), Lipo-C, Zepbound prescriptions, and peptides - all powerful aids designed to support your goals and enhance your well-being. 

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WOMEN'S HEALTH + HRT

 

In our Hormone Replacement Therapy consultations, we discuss all the possibilities: progesterone, testosterone, hcg, thyroid, cortisol, estrogen, peptides, vitamin therapy and more. We offer a tailored & functional approach, taking your labs in house and offering affordable membership options with local support. Book your lab appointment for bloodwork data and then your followup consult to see our bioidentical hormone options: creams, oral, injections, or pellets.  

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Offering allergy testing! (IgE + IgG) in house as part of our holistic assessments - book as a standalone or in conjunction with you other health consultations. 

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IV/IM MICRONUTRIENT THERAPY

AND NAD+ THERAPY 

 IV Micro-nutrient Therapy Infusions are powerful tools with a proven track record for promoting anti-aging effects, boosting immunity, reducing anxiety, and even supporting reversing the effects of a night out. 

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Available to purchase per IV, in packs of 5, or in membership:

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Monthly IV Infusion Membership
- Includes one custom IV Infusion each month + one free B12 shot each month, upgrades available
- 10% Off all other nutrient wellness services + 10% Off all retail products

 

NAD+ THERAPY regulates repair of damaged DNA, aging, gene expression, and more. NAD+ supplementation can benefit longevity, aging, neurodegenerative disorders such as Alzheimer's, Parkinson's, and MS as well as addiction recovery.

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Monthly NAD+ Infusion Membership
- Includes one NAD+ 250mg Infusion (upgrades available to 500mg + 1000mg) each month

+ one free B12 shot each month
- 10% Off all other nutrient wellness services + 10% Off all retail products

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NAD+ is also available per injection, infusion IV, or vial. Discounts available if purchased in pack of 4+.

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​​Want the convenience of an IV in your home, office, or event? 

​​Check out 417 Refine Concierge for Mobile IVs!​

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MEN'S HEALTH + HRT

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In our Hormone Replacement Therapy consultations, we discuss all the possibilities: low testosterone, hcg, growth hormone, thyroid, cortisol, estradiol, peptides, vitamin therapy and more. We offer a tailored & functional approach, taking your labs in house and offering affordable membership options with local support. Book your lab appointment for bloodwork data and then your followup consult to see our bioidentical hormone options: injections, creams, oral, pellets.  â€‹

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Offering allergy testing! (IgE + IgG) in house as part of our holistic assessments - book as a standalone or in conjunction with you other health consultations. 

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SEXUAL WELLNESS​

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Regain confidence and take control of your sexual health, even if other treatments haven’t worked. Our approach includes exploring cutting-edge injectable therapy and identifying root causes such as hormonal imbalances, circulation issues, or other factors. We then develop a personalized plan to restore your performance and confidence.

 

What We Offer:

  • Comprehensive, confidential consultations

  • Advanced therapies including penile injections, hormone optimization, and peptide treatments

  • Female/Male O Shot PRP non-surgical therapies to stimulate natural tissue regeneration

  • Proven medical solutions with lasting results: Increased sensitivity and stronger orgasm, enhanced vaginal tissue health and natural rejuvenation, improved urinary control and reduction in incontinence symptoms, increased tightness and girth

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NEW OFFERING - FIRST TEN TO BOOK O-SHOT TREATMENT RECEIVE $700 OFF 

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FACIALS + MICRONEEDLING

Revitalize your skin and defy aging with our facial treatments, including Custom Facials, Dermaplane Facials, Acne Treatment Facials, Hydrafacials, Micro-needling, Cryo-Facials -- all with optional paired LED light therapy. From gentle exfoliation and deep hydration to stimulating collagen production and reducing fine lines, each treatment is tailored to rejuvenate and nourish your skin from within.​​​​
 

ASK ABOUT OUR HYDRAFACIAL MEMBERSHIP 179/mo

INCLUDES SKINCARE AND ESTI DISCOUNTS

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Deluxe HydraFacial 45 mins

Includes deep cleanse, exfoliating, extracting impurities from the skin while simultaneously infusing nourishing ingredients to hydrate the skin. Includes Customized Booster + LED  light therapy​

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Platinum HydraFacial 60 mins

Includes all of the Deluxe HydraFacial plus Lymphatic  Drainage, choice of extraction tip or wet diamond micro-dermabrasion tip, Customized Booster, Eye or Lip Booster, + LED light therapy​​

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Custom Facial, Dermaplane, and Seasonal Facials 

(Or add-on dermaplane to another service)

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Cryo-Facial  | Joplin only

 

Pro- Microneedling Treatment

  • Silver Package | Includes cleansing, numbing, medical-grade microneedling at customized depth, Plated Calm Pump, and an Epionce Post-Recovery Care Kit to support healing

  • Gold Package | + PRP (Platelet-Rich Plasma), SkinBooster Brighten, or SkinBooster Tighten 

  • Platinum Package | + your choice of one premium enhancement: VAMP® PDRN, or Benev Exosomes, or SkinBooster Heighten - and enjoy 10% off all (plated) skincare day of service! 

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CHEMICAL PEELS

Transform your skin with variety of treatments, including with our preferred and customized chemical peels: VI Peel and BioRePeel treatments. Enhance your skin's radiance and texture with rejuvenating chemical peels, tailored to your unique skincare needs.

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BROW & LASH & WAX SERVICES 

Indulge in the artistry of our expert brow services  and lash lift & tints. Let our licensed aesthetician enhance your natural beauty with meticulous shaping techniques including trimming, waxing, tinting, and lamination. Whether you crave bold, defined brows or a subtle, polished look, trust us to create the perfect frame for your face.

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We also offer FULL BODY waxing options including Brazilians.

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CONSULTS

Every great result starts with a personalized consultation. At 417 Refine, we take a comprehensive approach to cosmetic injectables, skincare, and overall skin health, ensuring your treatment plan is tailored specifically to you.

 

We combine expert guidance with advanced technology using the VISIA® Skin Analysis system, which provides a detailed look beneath the surface of your skin, evaluating:

  • Fine lines and wrinkles, pore size and texture

  • Sun damage and UV spots/pigmentation

  • Overall skin age and health and more 
     

This allows us to create a customized plan that may include injectables, medical-grade skincare, and treatments designed to improve both the appearance and long-term health of your skin - paired with your 417 Refine Prescription Treatment plan. 

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MEDICAL GRADE SKINCARE 

Elevate your skincare routine to the next level with our curated selection of medical-grade skincare products. Designed by experts and backed by science, these premium formulations deliver unparalleled results you can see and feel.

  •  SkinBetter

  • (Plated)

  • Hydrinity

  • Revitalash

  • Revision
  • Epionce

  • Nutrafol
     

If you want so say goodbye to guesswork as our licensed professionals help create a customized regimen for you - book a complimentary skincare consult! 

SPRINGFIELD

417 Refine Logo

2918 East Battlefield Rd

Springfield, MO 65804

(417) 221-6419

+ Offering Mobile Concierge!

JOPLIN

516 S Virginia Ave

Joplin, MO 64801

(417) 414-0148

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© 2026 By 417 Refine

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